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. Author manuscript; available in PMC: 2017 Oct 4.
Published in final edited form as: Psychopharmacology (Berl). 2016 Feb 12;233(10):1945–1962. doi: 10.1007/s00213-016-4235-8

Fig. 5.

Fig. 5

Validation of METH-induced expression of genes identified by microarray experiments using RT-PCR. Values represent means ± SEM in comparison to saline group. Consistent with microarray data, METH self-administration induced increases in the expression of C-jun and Crem transcription factors, Fst, Nts and Pdyn neuropeptides and Stx1A involved in the synaptic functions at 2 h, which were normalized at 24 h after cessation of drug exposure. N = 6 per group. * p < 0.05 in comparison to saline group (Student’s t-test). Figure adapted from Krasnova et al. 2013.