Table 4.

Multivariate analysis showing independence of the effect on lymph node metastasis

	Number of patients	Odds ratio	95% CI	P
Age		1.01	0.99–1.04	0.277
Tumor size		1.12	1.00–1.25	0.049
Tumor depth (pT)
T1	120 (26.1%)	1 (ref)
T2	62 (13.5%)	17.14	7.70–38.17	<0.001
T3	121 (26.4%)	33.99	14.87–77.71	<0.001
T4	156 (34.0%)	13.35	6.22–28.64	<0.001
Lauren classification
Intestinal	174 (37.9%)	1 (ref)
Diffuse + Mixed	285 (62.1%)	1.07	0.61–1.88	0.825
Slug composite score
Low	104 (22.7%)	1 (ref)	1.09–1.76
Mid	130 (28.3%)	1.33	0.67–2.63	0.413
High	225 (49.0%)	3.42	1.74–6.69	<0.001