. 2017 Oct 3;9:107. doi: 10.1186/s13148-017-0408-5

Table 4.

Pearson correlations of cord blood GABBR1 DNA methylation (average and separate CpG units) with infant HPA axis cortisol measurements in response to routine vaccination at 2 and 4 months of age

			GABBR1 DNA methylation
Child HPA axis stress response			CpG_1.2	CpG_3	CpG_6	CpG_8	CpG_9.10	CpG_11	CpG_14.15	CpG_16	CpG_17	Average GABBR1
2 M (n = 20)	AUCi	Pearson R	0.372	− 0.476	0.029	− 0.452	0.109	0.062	0.375	0.238	0.218	− 0.152
	AUCi	p value	0.141	0.053	0.924	0.091	0.678	0.826	0.153	0.375	0.418	0.547
	Initial response	Pearson R	0.141	− 0.47	0.092	− 0.270	0.120	− 0.004	0.448	0.125	0.172	− 0.098
	Initial response	p value	0.565	0.043	0.745	0.295	0.624	0.989	0.062	0.621	0.494	0.680
	Recovery slope	Pearson R	0.141	− 0.283	0.063	− 0.162	0.118	− 0.103	0.342	− 0.012	0.083	− 0.086
	Recovery slope	p value	0.576	0.255	0.830	0.550	0.641	0.716	0.179	0.964	0.751	0.727
4 M (n = 67)	AUCi	Pearson R	0.260	0.239	0.241	0.200	0.084	0.096	0.080	0.186	0.082	0.168
	AUCi	p value	0.041	0.079	0.091	0.150	0.538	0.487	0.553	0.177	0.547	0.189
	Initial response	Pearson R	0.392^a	0.215	0.35	0.3	0.166	0.184	0.077	0.160	0.136	0.202
	Initial response	p value	0.001	0.102	0.009	0.023	0.210	0.166	0.556	0.230	0.301	0.100
	Recovery slope	Pearson R	0.400^a	0.219	0.38	0.35	0.209	0.27	0.130	0.192	0.182	0.225
	Recovery slope	p value	0.001	0.102	0.005	0.010	0.115	0.047	0.327	0.159	0.173	0.071

^aSignificant at the α level of 0.0019, corrected for 27 tests (3 cortisol variables and 9 CpG sites)