Table 7.
The receptor complex components for protein-bound uremic toxins and their signal components may also be the key regulators for pathogenic signaling
| Protein | Gene | NCBI-Gene ID | PMID |
|---|---|---|---|
| Glycoprotein Gp60 | UL1 | 2657001 | 26925240 |
| Glycoprotein Gp30 | UL44 | 2952505 | 26925240 |
| Glycoprotein Gp18 | F857_gp18 | 14182318 | 26925240 |
| SPARC | P13K | 18708 | 14517321 |
| Akt | 207 | ||
| RhoA* | 387 | ||
| SMAD2 | 4087 | ||
| SMAD3 | 4088 | ||
| TAK1 | 7182 | ||
| TAB1 | 10454 | ||
| MKK4 | 841591 | ||
| FcRn | Numb | 8650 | 25674083 |
| α-adaptin | 101901253 | ||
| CDC42 | 998 | ||
| RhoA | 387 | ||
| PP2A*- | 843333 | ||
| Smart2/3 | -- | ||
| Ets* | 692446 | ||
| c-Jun* | 3725 | ||
| Fos* | 2353 | ||
| Elk* | 131096 | ||
| HIF1* | 3091 | ||
| STAT* | 6646 | ||
| CREB* | 1385 | ||
| Stathmin* | 3925 | ||
| PLA2* | 5320 | ||
| Cubilin-megalin complex | Ets | 692446 | 26055641 |
| c-Jun | 3725 | ||
| Fos | 2353 | ||
| Elk | 131096 | ||
| HIF1 | 3091 | ||
| STAT | 6646 | ||
| CREB | 1385 | ||
| Stathmin | 3925 | ||
| PLA2 | 5320 | ||
| RAGE | Bad | 572 | 22934052 |
| Caspase8 | 841 | ||
| Gsk3 | 2932 | ||
| MDM2 | 4193 | ||
| NF-κB | 4790 | ||
| PP2A | 843333 | ||
| Ets | 692446 | ||
| c-Jun | 3725 | ||
| Fos | 2353 | ||
| Elk | 131096 | ||
| HIF1 | 3091 | ||
| STAT | 6646 | ||
| CREB | 1385 | ||
| Stathmin | 3925 | ||
| PLA2 | 5320 | ||
| NFAT | 32321 | ||
| Sap1 | 2539285 | ||
| Max | 4149 | ||
| Myc | 4609 | ||
| p53 | 2768677 | ||
| CHOP | 1649 | ||
| MEF2 | 853342 | ||
| ATF-2 | 1386 |