Table 9.
28 of the 169 genes have been identified in exosomes, which regulate the uremic toxins, the convertase of uremic toxins, the generation enzyme genes and the receptor complex components for protein-bound uremic toxins and their signal components
| Chemicals | Gene symbol | Gene ID |
|---|---|---|
| Uremic toxins (6) | ||
| β2-Microglobulin | B2M | 567 |
| Complement factor D | CFD | 1675 |
| Cystatin C | CST3 | 1471 |
| κ-Ig Light chain | IGK | 50820 |
| λ-Ig Light chain | IGL | 3535 |
| Retinol binding protein | RBP4 | 5950 |
| Convertases of uremic toxins (2) | ||
| Furin | FURIN | 5045 |
| ECE | ECE1 | 1899 |
| Enzymes of uremic toxins (18) | ||
| Adenosyl homocysteinase | AHCY | 191 |
| Putative adenosylhomocysteinase 2 | AHCYL1 | 10768 |
| Aldose reductase | AKR1B1 | 231 |
| Aldo-keto reductase family 1 member B10 | AKR1B10 | 57016 |
| Aldehyde dehydrogenase family 3 member B1 | ALDH3B1 | 221 |
| 4-trimethylaminobutyraldehyde dehydrogenase | ALDH9A1 | 223 |
| Aldehyde oxidase | AOX1 | 316 |
| S-methyl methionine--homocysteine S-methyltransferase | BHMT2 | 23743 |
| Aromatic-L-amino-acid decarboxylase | DDC | 1644 |
| Hypoxanthine-guanine phosphoribosyltransferase | HPRT1 | 3251 |
| 3-mercaptopyruvate sulfurtransferase | MPST | 4357 |
| 5′ (3′)-deoxyribonucleotidase, cytosolic type | NT5C | 30833 |
| 5′-nucleotidase | NT5E | 4907 |
| Purine nucleoside phosphorylase | PNP | 4860 |
| Serum paraoxonase/arylesterase 1 | PON1 | 5444 |
| Serum paraoxonase/lactonase 3 | PON3 | 5446 |
| Nicotinate-nucleotide pyrophosphorylase (carboxylating) | QPRT | 23475 |
| Xanthine dehydrogenase/oxidase | XDH | 7498 |
| Receptor complex (2) | ||
| FcRn | CASP8 | 841 |
| RAGE | CDC42 | 998 |