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Identified fusion genes and recovery rate of validated fusions among different tools. One hundred and twenty-six fusions were previously validated by RT-PCR. Five methods (fusionMap, deFuse, deFuse-0.81, confFuse-6.5, and confFuse-8) performed similarly in terms of recovery rate. confFuse generated much less fusion candidates than the others (higher specificity) while identifying comparable number of validated fusions (similar sensitivity).
