Table 1. Summary of available data for RhoA and Rac1 effector accumulation and furrowing phenotypes during cytokinesis in two key Caenorhabditis elegans cyk-4 GTPase-activating protein mutants.

CYK-4 variant	RhoA effector accumulation at furrow	Rac1 effector hyperaccumulation at furrow	Furrow ingression	Furrow ingression in the absence of Rac1	Furrow ingression in the absence of NOP-1	Furrow ingression in the absence of NOP-1 and Rac1
Wild-type	+++	Absent	Normal, complete	Normal, complete	Normal, complete	Normal, complete
E448K	*	Not determined	Slow, partial	Slow, complete	Absent	Absent
R459A	+	Not determined	Slow, partial	Slow, complete	Absent	Absent

*Conflicting data; see the “cyk-4 GAP mutants have multiple defects” section.

+++ Wild-type accumulation of myosin II, RhoA biosensor.

+ Reduced accumulation of myosin II, RhoA biosensor.