Table 1. Acute coronary syndrome medications.
Antiplatelet |
---|
Aspirin |
P 2Y 12 antagonists |
Clopidogrel a |
Prasugrel
a,
b (relatively contraindicated in patients who are at least
75 years old or whose body weight is less than 60 kg) |
Ticagrelor |
Cangrelor b |
Glycoprotein IIb/IIIa inhibitors |
Tirofiban b, c |
Eptifibatide b, c |
Abciximab b |
Anticoagulant |
Heparin b |
Enoxaparin (low-molecular-weight heparin) a, b, c |
Dalteparin (low-molecular-weight heparin) b |
Fondaparinux
c (in the US, use for acute coronary syndrome is
off-label) |
Argatroban b |
Bivalirudin
b,
c (vascular access site bleeding more often in
patients older than 65 years) |
Anti-ischemic |
Nitroglycerin |
Beta blocker
c (in the elderly, consider lower initial doses and
titrate to response) |
Adjunct |
Statins c |
Angiotensin-converting enzyme inhibitor c |
Angiotensin receptor blocker c |
aNeed for age-based dose adjustment. bNeed for weight-based dose adjustment. cNeed for renal-based dose adjustment.