Figure 7.

Scoring of the phase behavior of mAb in a pH range from 5 to 9, a protein concentration range from 120 to 225 mg/ml, and (a) 0–250 mM glycine, (b) 0–2 (m/V)% PEG4000, and (c) 0–160 mM Na₂SO₄ visualized as 3D plots. The plates were stored at a constant temperature of 20°C. The scoring was done after 40 d of incubation based on the visual evaluation of the pictures taken by the Rock Imager. The blue round symbols stand for samples containing soluble mAb molecules, the small light red squares symbolize light precipitation in the middle of the well, and the dark red squares symbolize heavy precipitation.