Figure 3.

AGuIX@SH NPs synthesis and characterizations.

Notes: (A) Reaction of the amino group with the Traut’s reagent (PBS, pH =8, [Gd³⁺] =80 mM, RT, one Traut’s reagent for one Gd). (B) Thiol quantification on AGuIX@SH using the Ellman’s reagent and absorbance measurements, n(Gd³⁺) =0.3 µmol in PBS (pH =8), 15 min, RT. The change of slope indicates that there are ~30 nmol of thiol in the solution (one SH for one particle).

Abbreviations: NP, nanoparticle; PBS, phosphate-buffered saline; RT, room temperature.