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. 2017 Sep 27;13:2477–2487. doi: 10.2147/NDT.S145069

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© 2017 Li et al. This work is published and licensed by Dove Medical Press Limited

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Artesunate prevented rats from the clozapine-induced plasma triglyceride increase.

Notes: Rats were intraperitoneally given saline, clozapine, artesunate, or clozapine + artesunate for 6 weeks. At the end, the rats were deeply anesthetized with sodium pentobarbital, and blood sample was taken by intracardiac puncture and subjected to biochemical analyses for the measurement of plasma triglyceride (A) and total cholesterol (B). Data were expressed as means ± standard error of the mean, and analyzed by two-way ANOVA, followed by one-way ANOVA and Bonferroni post-tests. *p<0.05, compared to saline group.

Abbreviation: ANOVA, analysis of variance.