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. 2017 Sep 20;40(5):1335–1346. doi: 10.3892/ijmm.2017.3144

Figure 6.

Figure 6

The role of NF-κB in tumor necrosis factor α (TNFα)-induced expression of interleukin-1β (IL-8), monocyte chemotactic protein-1 (MCP-1), intercellular cell adhesion molecule-1 (ICAM-1) and MMP9 in HaCaT cells. (A–C) RT-qPCR analysis showing the effects of BAY11-7082 on the TNFα-induced changes in the mRNA levels of (A) IL-8, (B) MCP-1 and (C) ICAM-1 in HaCaT cells. (D and E) Immunoblotting (D) or RT-qPCR (E) assays showing the effect of BAY11-7082 on the TNFα-induced epression of MMP9 at protein or mRNA level in HaCaT cells. All the bars represent the means ± SD of 3 independent experiments, and normalized to the GAPDH mRNA level with the value in the TNFα-free group set as 1 arbitrarily (A–C and E) or to β-actin level (D). **p<0.01.