Figure 4.

Vincristine (VCR) treatment at low concentration and for a short time did not inhibit cell proliferation. (A) The proliferation of RAW264.7 cells was assayed over a 48 h period with VCR of different concentration, and the data shown are means ± SD from 3 independent experiments (^**P<0.01 and ^***P<0.001). (B) RAW264.7 cells were primed for 24 h with VCR at different concentrations, and cell morphology was observed under a light microscope (original magnification, ×100). Similar observations were obtained from three independent experiments. OD, optical density.