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. 2017 Sep 7;40(5):1357–1364. doi: 10.3892/ijmm.2017.3126

Table IV.

Top 10 genes ranked by BC.

Gene BC EXP Degree P-value Qval Qpval τ2
ESR1 4.03E−01 26 1.60E−02 2.73E+00 4.35E−01 0
EP300 1.90E−01 + 19 4.86E−02 1.12E+00 7.73E−01 0
TP53 6.70E−02 Null 10
SMAD3 1.02E−01 Null 9
EGFR 7.40E−02 Null 9
FN1 1.33E−01 + 8 9.80E−03 2.63E+00 4.52E−01 0
SRC 9.92E−02 Null 8
PRKCA 8.43E−02 Null 8
DDX5 6.33E−02 8 1.00E−03 1.04E+00 7.91E−01 0
EPOR 2.35E−02 + 8 3.80E−02 6.93E−01 8.75E−01 0

'+' in the column 'EXP' indicates upregulation in metastatic OS, while '−' indicates downregulation and 'null' indicates no differential expression. BC, betweenness centrality; OS, osteosarcoma.