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. 2017 Oct 4;12(10):e0185728. doi: 10.1371/journal.pone.0185728

Table 4. Patients who received a second DAA treatment, by type of first regimen and HCV genotype (n = 72 patients).

Second DAA Regimen
First DAA Regimen SOF+DCV
Number of patients (%)
SOF+LDV
Number of patients (%)
Other Regimens
N. patients
38
(52.7%)
Gt1 Gt2 Gt3 Gt4 N. patients
27
(37.5%)
Gt1 Gt3 Gt4 N. patients
7
(9.7%)
Gt1, Gt3, Gt4
SOF+RBV 29 7* (24.1) 3 (10.3) 19* (65.5) 14 11 (78.6) 1(7.1) 2(14.2) 1 PEG+SOF+RBV
(Gt3)
SOF+SMV 9 7 (77.8) - - 2 (22.2) 13 13* (100) 2 3D (Gt1);
2D (Gt4)
SOF+LDV - - - - - - - - - 4 3D; (Gt1)
SOF+SIM
(Gt1 and Gt4)
SVR12 36
(94.7)
13 (92.8) 3
(100)
18
(94.7)
2
(100)
26
(96.3)
23
(95.8)
1
(100)
2
(100)
8
(100)

*1 patient Gt1 and 1 patient Gt3 did not achieved the SVR12 to the retreatment with SOF+DCV; 1 patient Gt1 did not achieved the SVR12 to the retreatment with SOF+LDV