Table 1. Characteristics of Electronic Symptom Monitoring and Management Systems for Home Use in Patients receiving Chemotherapy.

System and Reference	Origin	Platform	Symptom Reporting and Monitoring	Alerts	Self-care messages/ Library or Information Resource	Reports	Reminders	Clinician Interface
Symptom Tracking and Reporting (STAR)11,21	Memorial Sloan Kettering Cancer Center NYC, NY, USA	Web portal at home	Adapted CTCAE for self-report; timing not specified	Email	No/No	Longitudinal reports viewed by patient and clinician	Email reminders	Clinician could access and follow-up with patient
WebChoice10	University Hospital Oslo, Norway	Web Site	Symptoms and Quality of Life; timing not specified	No	Tailored/ Information page with links	No	No –Voluntary log in	Clinician could not access; follow-up occurred after patient emailed nurse
Symptom Care and Management System12	National University Cancer Institute Singapore	Web site could use mobile device	Vital signs and 5 symptoms (if screen positive); daily reporting	No	Standard/Educational module	In real time with 7 days of data	Not reported	Clinician could access and follow-up with patient by video-conference only
t+ Medical Ltd 13	Oxford University, Oxford, UK	Mobile phone	Temperature and 5 symptoms (CTCAE); twice daily reporting	Pager	Tailored/No	Real time, cumulative	Not reported	Clinician access and follow-up with patient
Advanced Symptom Management System (ASyMS)9,14	Cancer Care Research Centre,University of Stirling, Stirling, UK	Mobile phone	Temperature and 6 symptoms; twice daily reporting and if sick	Pager	Tailored/No	Nurse views on web	Not reported	Clinician could access and follow-up with patient
Tele-oncology service using short message service (SMS) 15	National Cancer Centre Singapore	Mobile phone, short message service	Nausea and vomiting; daily reporting	Email	Tailored/No	Not reported	Short message service	Clinician could access and pharmacist follow-up with patient
Handheld Symptom Management System 16	UK based study, Universities Stirling, Glasgow	Personal Digital Assistant	Adapted C-SAS for report of 5 symptoms; at least once a day reporting	Pager or email	Tailored/No	Real time, Nurse views on web	Not reported	Clinician could access and follow-up with patient
Communicating Health Assisted by Technology Project (CHAT) 17	Ohio State University Comprehensive Cancer Center, Columbus, OH, USA	Personal Digital Assistant	Brief Pain Inventory, Fatigue Symptom Inventory, CESD, SF-36; weekly reporting	PDA alarm tells patient to call oncologist	No/No	Summary graph	Via PDA	No
Symptom Monitoring and Reporting System for Lung Cancer (SyMon-L) 18	Clinics in Cook County area (IL)	telephone-based interactive voice response (IVR) technology	13-item symptom survey (Functional Assessment of Cancer Therapy [FACT] and LungSymptom Index [FLSI]; weekly reporting	Email	No/No	Weekly automated delivery of paper report	Phone	Clinician could not access; follow-up in response to email alert
Telephone Linked Care for Cancer Symptom Monitoring; Automated Symptom Monitoring 1,19	Huntsman Cancer Institute, University of Utah College of Nursing, Salt Lake City, UT, USA	Interactive Voice response system	10 symptoms (1-10 numeric scale) with drill down if symptom present; daily reporting	Email or FAX	No/No	Embedded in alert	Automated	No
Health Buddy®20	James Graham Brown Cancer Center University of Louisville, Louisville, KY, USA	Electrical device that attaches to land-line phone	3-5 questions per day related to 29 symptoms	No	Tailored/No	No	Green light on device	Clinician could access day after symptom reporting and follow-up with patient
Home telehealth Program37	Veteran's Administration Medical Center Gainesville, FL USA	Electrical device that attaches to land-line phone	5 symptoms; daily	Computer system	Tailored/No	Not reported	Not reported	Clinician could not access; follow-up in response to alert

NOTE: CTCAE= Common Terminology Criteria for Adverse Events