Table 2.

Unstandardized coefficients of high anticholinergic burden when controlling for current symptom severity (PANSS total score) and antipsychotic dose (CPZeq)^a

	High Anticholinergic Burden (ADSb score of ≥ 4)
	Schizophrenia (N=206)		Schizoaffective Disorder (N = 131)		Psychotic Bipolar Disorder (N=146)
	Unstandardized Coefficients (B)	p-value	Unstandardized Coefficients (B)	p-value	Unstandardized Coefficients (B)	p-value
Composite BACSc	−0.576	0.004	−0.08	0.725	−0.104	0.671
Verbal Memory	−0.55	0.003	−0.152	0.557	−0.297	0.231
Digit Sequencing	−0.148	0.387	−0.146	0.482	−0.103	0.622
Token Motor	−0.523	0.003	0.044	0.823	−0.061	0.791
Verbal Fluency	−0.207	0.225	0.123	0.545	−0.086	0.698
Symbol Coding	−0.512	0.006	−0.299	0.163	0.142	0.536
Tower of London	−0.386	0.061	0.056	0.804	−0.001	0.995

^aBold: statistically significant (p-value < 0.05)

^bADS=Anticholinergic Drug Scale

^cBACS=Brief Assessment of Cognition in Schizophrenia