Skip to main content
. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Mol Cancer Ther. 2017 Jun 15;16(10):2191–2200. doi: 10.1158/1535-7163.MCT-16-0907

Figure 3. 225Ac-IA-TLs causes BBB opening in immunocompetent mice.

Figure 3

(A) Extravasation of intravenously injected Evans blue dye shows clear BBB opening in immunocompetent mice infused with 225Ac-IA-TLs 2 days, 5 Days and 10 days (n=3) when compared to immunocompetent mice that were infused with saline (n=3). Yellow arrows indicate site of intracranial injection. (B) and (C) Area and intensity of extravasated Evans blue dye was also found to be greater in mice intracranially infused with 225Ac-IA-TLs when compared to mice intracranially infused with saline upto 10 days post infusion.