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. 2017 Sep 15;49(9):e377. doi: 10.1038/emm.2017.135

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Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/4.0/

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Delivery of N(−) or NM to adult mice decreased white adipose tissue mass. (a) Images of abdominal fat (stars) among treatment groups. (b) Quantification of the abdominal fat. An obvious decrease in WAT mass was found after FST vector delivery (24.3% of the control). Although not as obvious as FST, the WAT mass of N(−) (48.8% of the control) and NM were significantly decreased (57.1% of the control). The WAT mass of the FST-I-I group did not change compared with the control (98% of the control). (c) The H&E staining of white adipose tissue (20 ×), scale bar: 100 μm. N=5, *P<0.05, **P<0.01 and *** P<0.001 compared with the control ICR mice.