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. 2017 Sep 22;49(9):e380. doi: 10.1038/emm.2017.140

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Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/

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TSG-6 improves histomorphology and function of livers with chronic damage. (a) Survival rates of MCDE-fed mice treated with vehicle or TSG-6 were plotted (CON group: n=4, M+V group: n=12, M+TSG-6 groups: n=6). (b) Liver morphology was assessed by H&E staining of liver sections from representative CON and MCDE groups treated with saline (M+V) or TSG-6 (M+TSG-6) (X40). (c) The LW/BW, serum levels of ALT and AST and TG levels in the livers of mice treated with vehicle or MCDE with or without TSG-6 (50 ng). The results were plotted as the mean±s.d. (n⩾4 mice per group) (*P<0.05). (d, e) IHC for active CASPASE-3 (d) and KI67 (e) in liver sections from the representative CON, M+V and M+TSG-6 groups (X40).