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. 2017 Sep 29;49(9):e381. doi: 10.1038/emm.2017.144

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Copyright © 2017 The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/

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Resveratrol treatment reduces the numbers of plasma cells (PCs) in the spleen and bone marrow of MRL/lpr mice. Enzyme-linked immunospot (ELISPOT) assays to quantify the numbers of PCs of (a) dsDNA-PCs, (b) IgG-PCs and (c) IgM-PCs in the spleen (left, 5 × 10³ splenocytes) and bone marrow (right, 2 × 10⁴ bone marrow (BM) cells) of control (empty circle) and resveratrol-treated (solid circle) MRL/lpr mice. *P<0.05, ***P<0.001, NS indicates no significance.