Fig. 2. Structural characterization of BKM120-loaded HE₁₂–SNAs. (a) Agarose gel electrophoresis (AGE) analysis of drug-loaded nanoparticles showing intact structures with no observed side products. (b) Dynamic light scattering (DLS) data showing a highly monodisperse population of drug-loaded nanoparticles in solution. (c) Atomic force microscopy (AFM) image showing a spherical nearly monodisperse population of drug-loaded products on surface. (d) Transmission electron microscopy (TEM) image of drug-loaded products reflecting highly monodisperse structures. Scale bars = 200 nm.