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. 2017 Jan 13;41(4):548–555. doi: 10.1016/j.jgr.2016.11.003

Fig. 1.

Figure 1

Rg3-RGE inhibits collagen-induced platelet aggregation. (A) Washed platelets were pretreated with Rg3-RGE or vehicle for 2 min in the presence of 1mM CaCl2, and stimulated with collagen for 5 min. (B) After the platelet aggregation reaction, scanning electron microscopy was performed. Representative scanning electron microscopy images of platelets with (a) no treatment, (b) treated with collagen 1.25 μg/mL, (c) treated with Rg3-RGE 50 μg/mL + collagen 1.25 μg/mL, (d) treated with 100 μg/mL Rg3-RGE + collagen 1.25 μg/mL, and (e) treated with 200 μg/mL Rg3-RGE + collagen 1.25 μg/mL. Graph represents the mean ± SD of at least four independent experiments. **p < 0.01, ***p < 0.001 compared to the agonist control. Rg3-RGE, Rg3-enriched red ginseng extract; SD, standard deviation.