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. 2017 Jan 24;41(4):589–594. doi: 10.1016/j.jgr.2017.01.010

Table 1.

Effects of ginsenosides in in vivo models of disease

Disease Ginsenoside Effective target Experiment model Ref.
Cardiovascular disease Rb1 Myocardial infarction Rat [51]
Re Cardiomyocyte Human, cat [52]
Rg1 Ventricular hypertrophy Rat [53]
Rg3 Vascular smooth muscle Rat and mice [54]
Stroke Rd National Institutes of Health Stroke Scale human [55]
Rg1 Formation of new synapses, cerebral cortex Mice [56]
Hippocampus Rat [57]
Diabetes Rb1 Antiobesity and antihyperglycemic effect Rat [58]
Re Antiobesity Mice [59]
Rg3 Insulin signaling and glucose uptake Rat [60]
Rheumatoid arthritis Rb1 Collagen Mice [39]
Osteoporosis Rg1 Osteoblast Rat [61]
Rb1 Osteoblast Rat [61]
Rb2 Bone mass Mice [62]
Erectile dysfunction Rg3 Corpus cavernosum Rat [63]
Re Corpus cavernosum Rat [64]
Rg1 Testosterone level, corpus cavernosum Mice [65]
Asthma Rb1 Bronchoalveolar lavage fluid Mice [66]
Rh2 Bronchoalveolar lavage fluid, lung Mice [67]