Table 1.
Disease | Ginsenoside | Effective target | Experiment model | Ref. |
---|---|---|---|---|
Cardiovascular disease | Rb1 | Myocardial infarction | Rat | [51] |
Re | Cardiomyocyte | Human, cat | [52] | |
Rg1 | Ventricular hypertrophy | Rat | [53] | |
Rg3 | Vascular smooth muscle | Rat and mice | [54] | |
Stroke | Rd | National Institutes of Health Stroke Scale | human | [55] |
Rg1 | Formation of new synapses, cerebral cortex | Mice | [56] | |
Hippocampus | Rat | [57] | ||
Diabetes | Rb1 | Antiobesity and antihyperglycemic effect | Rat | [58] |
Re | Antiobesity | Mice | [59] | |
Rg3 | Insulin signaling and glucose uptake | Rat | [60] | |
Rheumatoid arthritis | Rb1 | Collagen | Mice | [39] |
Osteoporosis | Rg1 | Osteoblast | Rat | [61] |
Rb1 | Osteoblast | Rat | [61] | |
Rb2 | Bone mass | Mice | [62] | |
Erectile dysfunction | Rg3 | Corpus cavernosum | Rat | [63] |
Re | Corpus cavernosum | Rat | [64] | |
Rg1 | Testosterone level, corpus cavernosum | Mice | [65] | |
Asthma | Rb1 | Bronchoalveolar lavage fluid | Mice | [66] |
Rh2 | Bronchoalveolar lavage fluid, lung | Mice | [67] |