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. 2017 Oct 4;37(40):9603–9613. doi: 10.1523/JNEUROSCI.3218-16.2017

Figure 2.

Figure 2.

Clinical evidence. Full NCC. A, Complete bilateral prefrontal lobectomy does not noticeably change the level of consciousness. Top row, Bilateral views of the resected left and right frontal lobes (Brickner, 1936). Bottom row, Postmortem lateral views of both hemispheres (Brickner, 1952). B, Anoxic lesions of posterior corpus callosum predict permanent VS after head trauma (Kampfl et al., 1998). C, Lesions of posterior corpus callosum, with restricted diffusion extending to parieto-temporo-occipital regions, predict permanent coma after anoxic brain damage (Bianchi and Sims, 2008). Content-specific NCC. D, A recent study suggests that intrusive thoughts can be elicited by electrical stimulation of anterior cingulate cortex (Popa et al., 2016). Eliciting any experience is, however, far more common when stimulating posterior than anterior cortical structures (Selimbeyoglu and Parvizi, 2010). E, F, Direct electrical brain stimulation (DES) supports a causal role for different parts of the posterior cortex in specifying conscious content, for example, the right FFA in contributing to face percepts (Rangarajan et al., 2014) (E) and the parietal cortex contributing the feeling of intention to move (F) (Desmurget et al., 2013). SF, Superior frontal sulcus; MF, middle frontal sulcus; IF, inferior frontal sulcus; DWI, diffusion weighted imaging.