Broadening of APs during repetitive stimulation. A, First and 15th APs evoked by 5 Hz stimulation in a small-diameter, capsaicin-sensitive DRG neuron. APs were evoked by a 0.5 ms 1.7 nA current injection. B, Time course of AP broadening with stimulation at frequencies from 1 to 20 Hz. Symbols show mean ± SEM for determinations at 1, 5, 10, and 20 Hz, each determined in 13 neurons.