Table 2. Cox proportional hazard models for conversion to MCI or dementia.
hazard ratio (SE) p | ||||
---|---|---|---|---|
| ||||
model 1† | model 2‡ | model 3§ | ||
Age | 1.06 (0.003) < 0.01 | 1.05 (0.003) < 0.01 | 1.04 (0.003) < 0.01 | |
Male | 1.29 (0.07) < 0.01 | 1.17 (0.07) 0.004 | 1.01 (0.07) 0.92 | |
Education | 0.96 (0.01) < 0.01 | 1.02 (0.01) 0.107 | 1.03 (0.01) < 0.01 | |
Level of independence | 2 | 2.13 (0.32) < 0.01 | 1.83 (0.28) < 0.01 | 1.62 (0.25) < 0.002 |
3 | 1.89 (0.48) 0.01 | 2.07 (0.53) < 0.01 | 1.78 (0.46) 0.02 | |
4 | 2.10 (1.25) 0.21 | 2.40 (1.43) 0.14 | 1.65 (0.99) 0.40 | |
FAQ total | 1.02 (0.003) < 0.01 | 1.01 (0.003) < 0.01 | 1.01 (0.004) 0.01 | |
GDS | 1.11 (0.003) < 0.01 | 1.10 (0.004) < 0.01 | 1.10 (0.13) < 0.01 | |
MMSE | 0.94 (0.02) 0.001 | 0.97 (0.02) 0.17 | ||
Logical memory | 0.93 (0.01) < 0.01 | 0.94 (0.01) < 0.01 | ||
Boston | 0.97 (0.01) < 0.01 | 1.09 (0.01) 0.44 | ||
Category fluency (animals) | 0.98 (0.01) 0.01 | |||
Category fluency (vegetables) | 0.95 (0.01) < 0.01 | |||
Trails B–A | 1.00 (0.001) 0.115 | |||
Digit span forward | 1.02 (0.02) 0.286 | |||
Digit span backward | 0.99 (0.02) 0.709 | |||
WAIS | 0.98 (0.003) < 0.01 |
Model 1: adjusted for baseline age, sex, years of education, and total FAQ.
Model 2: model 1 + MMSE, logical memory, Boston naming.
Model 3: model 1 + model 2 + TMT B–A, animal and vegetable category fluencies, and digit span forward and backward.