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. 2017 Jul 20;8(9):6354–6358. doi: 10.1039/c7sc02405c

Table 1. Optimization of catalyst conditions for cyclization reaction in water at room temperature.

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Entry Conditions Result
1 LAuCl (1000 ppm) + AgBF4 (1000 ppm) NR
2 LAuCl (1000 ppm) + AgOTf (1000 ppm) NR
3 LAuCl (1000 ppm) + AgSbF6 (1000 ppm) NR
4 LAuCl (1000 ppm) + AgBF4 (1000 ppm) + TFA (1 equiv.) 56% (5 d)
5 LAuCl (1000 ppm) + AgOTf (1000 ppm) + TFA (1 equiv.) Trace
6 LAuCl (1000 ppm) + AgSbF6 (1000 ppm) + TFA (1 equiv.) 71% (4 d)
7 LAuCl (1000 ppm) + AgSbF6 (2000 ppm) + TFA (2 equiv.) 98%