Table 1. Somatic alterations identified in the left frontal pleomorphic xanthoastrocytoma and right cerebellar diffuse astrocytoma.

Pleomorphic xanthoastrocytoma, left frontal lobe
Variant	Reference transcript	Classification
CDKN2A/B homozygous deletion	N/A	Pathogenic
BRAF p.V600E	NM_004333	Pathogenic
CDH1 p.V55G	NM_004360	VUS
SPTA1 p.T1953I	NM_003126	VUS
Diffuse astrocytoma, right cerebellum
Variant	Reference transcript	Classification
CDKN2A/B homozygous deletion	N/A	Pathogenic
ATRX p.G1152fs	NM_000489	Pathogenic
NF1 p.L1246fs	NM_001042492	Pathogenic
NF1 p.W1685fs	NM_001042492	Pathogenic
PTPN11 p.T73I	NM_002834	Pathogenic

fs = frameshift; N/A = not applicable; VUS = variant of unknown significance.