Table 2.

Sensitivities, specificities, and AUC of PAX1 and SOX1 methylation in detecting CRC tumor (n=41)

Detection modality	Cancer		Paracancer		Sensitivity %	Specificity %	AUC	95% CI	P-value*
	U	M	U	M
PAX1	13	28	36	5	68.3	87.8	0.743	0.627–0.858	<0.001
SOX1	13	28	41	0	68.3	100.0	0.798	0.689–0.907	<0.001

Note:

^*Calculated by χ² test.

Abbreviations: AUC, areas under the curve; CRC, colorectal cancer; M, methylated; PAX1, paired boxed gene 1; SOX1, sex-determining region Y-related high-mobility group box 1; U, unmethylated.