Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 30;11:1769–1775. doi: 10.2147/OPTH.S148650

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Ayaki et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Presence of DED-related signs in (A) non-DED and (B) DED patients. Seasonal variation was observed in BUT and SPK in the DED patients. Seasonal variation in all signs except for the Schirmer test was observed in the non-DED subjects. ^*P<0.05 when the season with the most severe symptoms was compared to the season with the least severe symptoms (chi-square test).

Abbreviations: BUT, tear break-up time; DED, dry eye disease; MBI, maximum blinking interval; SPK, superficial punctuate keratitis.