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. 2017 Sep 7;12(10):1615–1623. doi: 10.2215/CJN.02510317

Table 2.

Sustained virologic response rate by genotype and regimen used

Genotype Total Treated, N Total with Sustained Virologic Response, N Sustained Virologic Response Rate, % Early Discontinuation, N (%)
Genotype 1Aa overall 54 45 83 3 (6)
 Sofosbuvir/ribavirin ×24 wk 2 2 100
 Sofosbuvir/simeprevir ×12 wk 32 25 78
 Sofosbuvir/simeprevir ×24 wk 1 1 100
 Sofosbuvir/ledipasvir ×12 wk 11 9 82
 Sofosbuvir/ledipasvir ×24 wk 4 4 100
 Sofosbuvir/ledipasvir/ribavirin ×12 wk 2 2 100
 Sofosbuvir/simeprevir/ribavirin ×12 wk 2 2 100
Genotype 1B overall 18 16 89 2 (11)
 Sofosbuvir/ribavirin ×12 wk 1 1 100
 Sofosbuvir/ribavirin ×24 wk 2 1 50
 Sofosbuvir/simeprevir ×12 wk 9 8 89
 Sofosbuvir/ledipasvir ×12 wk 5 5 100
 Sofosbuvir/simeprevir/ribavirin ×12 wk 1 1 100
Genotype 2 14 12 86 1 (7)
 Sofosbuvir/ribavirin ×12 wk 14 12 86
Genotype 3 7 3 43 2 (28)
 Sofosbuvir/ribavirin ×12 wk 1 0 0
 Sofosbuvir/ribavirin ×24 wk 6 3 50
Genotype 4 5 3 60 0 (0%)
 Sofosbuvir/ribavirin ×24 wk 2 1 50
 Sofosbuvir/ledipasvir ×12 wk 3 2 67
Total 98 79 81 8 (8)
a

Includes both genotype 1A and genotype 1 nonsubtypable.