Table 2.
Genotype | Total Treated, N | Total with Sustained Virologic Response, N | Sustained Virologic Response Rate, % | Early Discontinuation, N (%) |
---|---|---|---|---|
Genotype 1Aa overall | 54 | 45 | 83 | 3 (6) |
Sofosbuvir/ribavirin ×24 wk | 2 | 2 | 100 | |
Sofosbuvir/simeprevir ×12 wk | 32 | 25 | 78 | |
Sofosbuvir/simeprevir ×24 wk | 1 | 1 | 100 | |
Sofosbuvir/ledipasvir ×12 wk | 11 | 9 | 82 | |
Sofosbuvir/ledipasvir ×24 wk | 4 | 4 | 100 | |
Sofosbuvir/ledipasvir/ribavirin ×12 wk | 2 | 2 | 100 | |
Sofosbuvir/simeprevir/ribavirin ×12 wk | 2 | 2 | 100 | |
Genotype 1B overall | 18 | 16 | 89 | 2 (11) |
Sofosbuvir/ribavirin ×12 wk | 1 | 1 | 100 | |
Sofosbuvir/ribavirin ×24 wk | 2 | 1 | 50 | |
Sofosbuvir/simeprevir ×12 wk | 9 | 8 | 89 | |
Sofosbuvir/ledipasvir ×12 wk | 5 | 5 | 100 | |
Sofosbuvir/simeprevir/ribavirin ×12 wk | 1 | 1 | 100 | |
Genotype 2 | 14 | 12 | 86 | 1 (7) |
Sofosbuvir/ribavirin ×12 wk | 14 | 12 | 86 | |
Genotype 3 | 7 | 3 | 43 | 2 (28) |
Sofosbuvir/ribavirin ×12 wk | 1 | 0 | 0 | |
Sofosbuvir/ribavirin ×24 wk | 6 | 3 | 50 | |
Genotype 4 | 5 | 3 | 60 | 0 (0%) |
Sofosbuvir/ribavirin ×24 wk | 2 | 1 | 50 | |
Sofosbuvir/ledipasvir ×12 wk | 3 | 2 | 67 | |
Total | 98 | 79 | 81 | 8 (8) |
Includes both genotype 1A and genotype 1 nonsubtypable.