Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A) Synthesis of aldehyde-functionalized MSNs, yielding MSN-CHO (leftmost reaction); attachment of isoniazid (INH) onto the surface of the aldehyde-modified nanoparticles, yielding MSN-CHO-INH (middle reaction); and release of the INH from MSN-CHO-INH by hydrolysis at acid pH (rightmost reaction). B) Assembly of copolymer PEI-PEG on the pH-responsive INH-loaded MSNs, yielding MSN-CHO-INH-PEI-PEG.
