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pH-stimulated release of INH from INH-loaded MSNs. UV-vis spectra of supernatants after washing INH-loaded nanoparticles with PBS (black trace) or with 0.1 N HCl (red trace) demonstrating release of INH under acidic conditions for both A) MSN-CHO-INH- and B) SMSN-CHO-INH. The analysis was repeated 2 times with MSN-CHO-INH and 2 times with SMSN-CHO-INH with similar results.
