Table 5. 15 central nodes with the highest degree scores in trastuzumab treated SKBR3 and BT474 miRNA networks.

All the nodes values were statistically significant with P-value <0.05.

Node name (miRNA ID)	Degree centrality score in SKBR3 network	Node name (miRNA ID)	Degree centrality score in BT474 network
hsa-miR-3976	9	hsa-miR-3671	19
hsa-miR-548b-5p	9	hsa-miR-4474-5p	16
hsa-miR-4480	9	hsa-miR-559	15
hsa-miR-548d-5p	8	hsa-miR-4517	15
hsa-miR-3194-5p	8	hsa-miR-485-5p	14
hsa-miR-4259	8	hsa-miR-558	13
hsa-miR-519e-5p	8	hsa-miR-29b-2-5p	13
hsa-miR-4478	8	hsa-miR-150-3p	12
hsa-miR-4496	7	hsa-miR-411-3p	12
hsa-miR-4635	7	hsa-miR-526b-3p	12
hsa-miR-581	7	hsa-miR-93-3p	11
hsa-miR-10b-5p	7	hsa-miR-551b-5p	10
hsa-miR-769-5p	6	hsa-miR-5579-3p	10
hsa-miR-190a-5p	6	hsa-miR-146b-5p	10
hsa-miR-216b	6	hsa-miR-3121-3p	10