Table 1.
Baseline characteristics of the participants
| Characteristics | Normal PTX3 (n = 30) | Abnormal PTX3 (n = 70) | P |
|---|---|---|---|
| Male [n (%)]* | 27 (90.0) | 62 (88.6) | > 0.990 |
| Smoking (yes) [n (%)]* | 16 (53.3) | 42 (60.0) | 0.660 |
| Hypertension (yes) [n (%)]* | 7 (23.3) | 29 (48.4) | 0.110 |
| Diabetes (yes) [n (%)]* | 6 (20.0) | 20 (28.6) | 0.460 |
| Affected with HLP (yes) [n (%)]* | 3 (10.0) | 3 (4.3) | 0.360 |
| Familial history of CAD (yes) [n (%)]* | 14 (46.7) | 28 (40.0) | 0.660 |
| Age (year) | 55.4 ± 12.5 (40.0-91.0) | 60.1 ± 10.7 (44.0-89.0) | 0.070 |
| Triglyceride (mg) | 148.9 ± 58.0 (38.0-266.0) | 130.3 ± 86.4 (37.0-552.0) | 0.210 |
| Cholesterol total (mg/dl) | 177.0 ± 34.7 (114.0-249.0) | 180.8 ± 32.4 (110.0-284.0) | 0.630 |
| Low density lipoprotein(mg/dl) | 105.6 ± 32.4 (49.0-160.0) | 103.7 ± 30.0 (50.0-190.0) | 0.780 |
| High density lipoprotein (mg/dl) | 40.7 ± 12.3 (5.1-69.0) | 43.4 ± 12.5 (23.0-79.0) | 0.310 |
| Uric acid (mg/dl) | 5.5 ± 1.4 (2.2-7.9) | 6.8 ± 11.6 (2.5-100.0) | 0.360 |
| Door to balloon (min) | 65.5 ± 28.7 (30.0-180.0) | 77.3 ± 35.7 (30.0-240.0) | 0.080 |
| Symptom to balloon (min) | 241.5 ± 171.1 (72.0-2656.0) | 274.1 ± 346.7 (90.0-2880.0) | 0.530 |
| Stents diameter (cm) | 2.9 ± 0.4 (2.2-3.5) | 3.0 ± 0.4 (2.5-4.0) | 0.260 |
| Creatinine (mg/dl) | 1.1 ± 0.1 (0.8-1.3) | 1.1 ± 0.2 (0.09-1.5) | 0.300 |
| Hemoglobin (Hb) (mg/d/l) | 13.4 ± 1.4 (8.9-16.3) | 12.7 ± 2.2 (7.3-16.8) | 0.058 |
| Systolic blood pressure (mmHg) | 124.0 ± 20.1 (95.0-185.0) | 124.1 ± 17.7 (90.0-165.0) | 0.980 |
| Heart rate | 74.6 ± 10.5 (50.0-93.0) | 82.9 ± 13.8 (45.0-119.0) | 0.002 |
| GRACE score | 148.0 ± 25.2 (98.0-215.0) | 177.0 ± 80.1 (120.0-798.0) | 0.008 |
| Lactate dehydrogenase (LDH)(u/l) | 551.0 ± 249.0 (284.0-1153.0) | 745.1 ± 611.4 (268.0-3561.0) | 0.026 |
| Creatine phosphokinase-MB (IU/l) | 71.6 ± 124.4 (5.0-542.0) | 127.4 ± 138.3 (10.0-550.0) | 0.052 |
| Total creatine phosphokinase (IU/l) | 491.5 ± 720.7 (32.0-2800.0) | 994.2 ± 1239.9 (53.0-5250.0) | 0.013 |
| Hemoglobin A1c (mmol/mol) | 6.2 ± 1.9 (4.3-13.8) | 6.1 ± 1.4 (4.0-11.8) | 0.079 |
| Duration of hospitalization (d) | 6.2 ± 2.6 (4.0-18.0) | 8.2 ± 3.7 (5.0-26.0) | 0.004 |
| Platelet count (109/l) | 191.0 ± 27.0 (122.0-250.0) | 216.1 ± 76.4 (117.0-666.0) | 0.018 |
| Platelet/lymphocyte ratio | 84.6 ± 26.3 (30.0-139.0) | 136.8 ± 67.0 (11.8-3561.0) | 0.001 |
| Troponin (ng/ml) | 66.1 ± 37.5 (3.0-172.0) | 74.5 ± 60.9 (2.0-193.0) | 0.120 |
PTX3: Pentraxin-3; HLP: Hyperlipidemia; CAD: Coronary artery disease; GRACE: Global registry of acute coronary events; SD: Standard deviation
Data are expressed as mean ± SD (range) and P-values are based on independent Student's t-test unless otherwise stated
*
P-values based on Fisher's exact test