Table 1. Comparison of the cefotaxime resistance mechanism, MIC value, and D-MSBL assay results for 58 E. coli derived from the BCs tested.
Isolate | Mechanism(s) of resistance | Phenotype | D-MSBL assay | |
---|---|---|---|---|
MIC (mg/L) | Categorya | Category | ||
1E | CTX-M-1 | 8 | R | R |
2E | CTX-M-15 | ≥64 | R | R |
3E | CTX-M-15 | ≥64 | R | R |
4E | - | ≤1 | S | S |
5E | - | ≤1 | S | S |
6E | - | ≤1 | S | S |
7E | CTX-M-15, SHV-11, TEM-1 | ≥64 | R | S |
8E | - | ≤1 | S | S |
9E | - | ≤1 | S | S |
10E | CTX-M-1 | ≥64 | R | S |
11E | - | ≤1 | S | S |
12E | CTX-M-27 | ≥64 | R | R |
13E | CTX-M-15 | ≥64 | R | R |
14E | CTX-M-15 | ≥64 | R | R |
15E | CTX-M-27 | ≥64 | R | R |
16E | - | ≤1 | S | R |
17E | - | ≤1 | S | S |
18E | CTX-M-15 | ≥64 | R | R |
19E | - | ≤1 | S | S |
20E | - | ≤1 | S | S |
21E | CTX-M-15 | ≥64 | R | R |
22E | CTX-M-15 | ≥64 | R | R |
23E | - | ≤1 | S | S |
24E | - | ≤1 | S | S |
25E | CTX-M-15 | ≥64 | R | R |
26E | CTX-M-15 | 4 | R | R |
27E | CTX-M-15, TEM-1 | ≥64 | R | R |
28E | - | ≤1 | S | S |
29E | - | ≤1 | S | S |
30E | CTX-M-15 | ≥64 | R | R |
31E | - | ≤1 | S | S |
32E | - | ≤1 | S | S |
33E | CTX-M-15 | ≥64 | R | R |
34E | CTX-M-27 | ≥64 | R | R |
35E | CTX-M-15 | ≥64 | R | R |
36E | - | ≤1 | S | S |
37E | - | ≤1 | S | S |
38E | - | ≤1 | S | S |
39E | - | ≤1 | S | S |
40E | - | ≤1 | S | S |
41E | - | ≤1 | S | S |
42E | - | ≤1 | S | S |
43E | - | ≤1 | S | S |
44E | - | ≤1 | S | S |
45E | - | ≤1 | S | S |
46E | - | ≤1 | S | S |
47E | - | ≤1 | S | S |
48E | - | ≤1 | S | S |
49E | - | ≤1 | S | S |
50E | - | ≤1 | S | S |
51E | - | ≤1 | S | S |
52E | - | ≤1 | S | S |
53E | - | ≤1 | S | S |
54E | - | ≤1 | S | S |
55E | - | ≤1 | S | S |
56E | - | ≤1 | S | S |
57E | - | ≤1 | S | S |
58E | - | ≤1 | S | S |
aThe MIC-based category was assessed according to the EUCAST guidelines version 6.0 2016 (S, ≤1 mg/L; R, >2 mg/L).