Table 1. Proteins involved in basic neutrophil functions.
| Gene | Common Protein Name(s) | Fold change for DMSO plus IFN-γ treatment versus DMSO treatment | ANOVA p-value |
|---|---|---|---|
| Proteins Involved in Neutrophil Transmigration | |||
| SELPLG | P Selectin Glycoprotein Ligand 1 | 1.21 | 0.000233 |
| ITGAM | Integrin Subunit αM/CD11b | 1.32 | 0.00902 |
| ITGAL | Integrin Subunit αL/CD11a | 1.84 | 0.000057 |
| ITGAX | Integrin Subunit αX/CD11c | 1.33 | 0.044166 |
| ITGA4 | Integrin Subunit α4 | 2.13 | 0.000031 |
| ITGB7 | Integrin Subunit β7 | 6.03 | 1.91E-07 |
| CEACAM1 | Receptor CD66a | 10.42 | 0.000003 |
| SELL | L-selectin | 3.31 | 0.000357 |
| SYK | Spleen Associated Tyrosine Kinase | -1.4 | 0.000142 |
| FGR | Fgr/FGR Proto-Oncogene, Src Family Tyrosine Kinase | -1.72 | 0.000025 |
| LYN | Lyn/LYN Proto-Oncogene, Src Family Tyrosine Kinase | 1.47 | 0.006379 |
| Proteins Involved in Chemotaxis | |||
| FPR1 | Formyl Peptide Receptor 1 | 1.66 | 0.000256 |
| FPR2 | Formyl Peptide Receptor 2 | 1.48 | 0.001889 |
| C3AR1 | Complement Component 3a Receptor 1 | 1.72 | 0.00363 |
| Proteins Involved in Phagocytosis | |||
| FCGR1A | Fc Gamma Receptor Ia/FcγRIA | 39.77 | 6.62E-07 |
| FCGR1B | Fc Gamma Receptor Ib/FcγRIB | 5.33 | 0.000007 |
| FCGR2A | Fcγ receptor IIa/FcγRIIA | 1.81 | 0.000032 |
| FCGR2B | Fcγ receptor IIb/FcγRIIB | 2.12 | 0.047517 |
| FCER1G | FcRγ | 1.48 | 0.000019 |
| Proteins involved in killing of pathogens | |||
| CYBB* | gp91-Phox | 1.19 | 0.010271 |
| NCF1* | p47-Phox | 1.51 | 0.025401 |
| LYZ | Lysozyme | 1.3 | 0.005024 |
| MPO | Myeloproxidase | -22.24 | 4.90E-07 |
aThis data was originally reported in Ellison MA et. al [12]