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. 2017 Oct 5;12(10):e0185956. doi: 10.1371/journal.pone.0185956

Table 3. Innate immune receptors.

Gene Common Protein Name(s) Fold change for DMSO plus IFN-γ treatment versus DMSO treatment ANOVA p-value
Toll Like Receptors
TLR4 Toll Like Receptor 4 2.14 0.000095
LY96 Lymphocyte Antigen 96 5.96 0.000844
TLR8 Toll Like Receptor 8 5.5 2.26E-07
TLR1 Toll Like Receptor 1 2.1 0.000152
TLR2 Toll Like Receptor 2 -1.5 0.020288
TLR3 Toll Like Receptor 3 1.44 0.012239
TLR9 Toll Like Receptor 9 -1.28 0.010429
MYD88 Myeloid Differentiation Primary Response 88 1.48 0.000243
RIPK1 Receptor-Interacting Protein 1 1.28 0.000001
RIPK2 Receptor-Interacting Protein 2 2.6 0.000913
TANK TRAF Family Member Associated NFKB Activator 1.48 0.002157
TRAF6 Interleukin-1 Signal Transducer 1.31 0.000461
IRAK3 IRAK-M -1.59 0.000721
Nod-Like Receptors, Inflammasome Components and AIM2
NOD1 Nucleotide Binding Oligomerization Domain Containing 1 1.38 0.003572
NLRP3 NLR Family, Pyrin Domain Containing 3 1.78 0.000068
CASP1 Caspase 1 5 5.47E-07
PYCARD PYD And CARD Domain Containing 1.37 0.000337
AIM2 Absent in Myeloma 2 24.56 0.000016
C-type lectins
CLEC7A C-Type Lectin Domain Family 7 Member A 1.6 0.001515
CLEC12A C-Type Lectin Domain Family 12 Member A -2.23 0.000048
CLEC4E C-Type Lectin Domain Family 4 Member E -1.43 0.028254
CLEC4D C-Type Lectin Domain Family 4 Member D -1.55 0.011814
CLEC2B C-Type Lectin Domain Family 2 Member B 8.15 8.55E-07
CLEC5A C-Type Lectin Domain Family 5 Member A -2.4 0.018912