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. 2017 Oct 5;12(10):e0185956. doi: 10.1371/journal.pone.0185956

Table 5. Proteins involved or potentially involved in antigen presentation by MHCII and MHCI.

Gene Common Protein Name(s) Fold change for DMSO plus IFN-γ treatment versus DMSO treatment ANOVA p-value
Proteins Involved or Potentially Involved in Antigen Presentation by MHCII
CIITA Class II, Major Histocompatibility Complex, Transactivator 6.35 0.000019
RFX5 Regulatory Factor X5 1.47 0.00167
HLA-DRA MHC, Class II, DR α 74.97 1.64E-07
HLA-DPA1 MHC, Class II, DP α 1 4.79 0.000027
HLA-DPB1 MHC, Class II, DP β 1 3.06 0.000052
CD74 Invariant Chain/iI/CD74 molecule 20.84 0.000005
HLA-DMA MHC, Class II, DM α 2.98 0.000059
HLA-DMB MHC, Class II, DM β 2.3 0.000002
CD86 CD86 antigen 1.5 0.000185
CD40 CD40 antigen 11.95 0.000004
PDCD1LG2 CD273 antigen 11.63 0.000007
CD274 CD274 antigen 35.96 3.44E-07
CTSB Cathepsin B 1.49 0.000812
CTSL1 Cathepsin L1 1.47 0.024585
CTSS Cathepsin S 2.97 3.69E-07
CTSO Cathepsin O 9.25 0.000004
CTSZ Cathepsin Z 1.78 0.000096
CTSA Cathepsin A 1.64 0.000184
Proteins Involved in Antigen Presentation by MHCI
B2M Beta-2-Microglobulin 1.54 0.000069
HLA-A MHC, Class I, A 2.36 0.000477
HLA-B MHC, Class I, B 2.55 0.000587
HLA-C MHC, Class I, C 2.01 0.000006
HLA-E MHC, Class I, E 2.73 3.05E-09
HLA-F MHC, Class I, F 1.62 0.000345
HLA-G MHC, Class I, G 2.21 0.000009
TAP1 Peptide Transporter Involved In Antigen Processing 1 20.86 1.57E-09
TAP2 Peptide Transporter Involved In Antigen Processing 2 11.88 1.60E-08
TAPBP TAP Binding Protein (Tapasin) 2.59 0.000004
PDIA3 Protein Disulfide Isomerase Family A Member 3 1.75 0.000288
CALR Calreticulin -1.24 0.002063