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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: AAPS PharmSciTech. 2016 Nov 30;18(6):1936–1945. doi: 10.1208/s12249-016-0672-2

Table I.

Physicochemical Properties of Δ9 & Δ8-Tetrahydrocannabinol1

Property Δ8-Tetrahydrocannabinol Δ9-Tetrahydrocannabinol
Molecular Weight 314.4 314.4
Log P 7.53 ± 0.36 7.68 ± 0.35
mLog P 3.96 3.96
Log D 7.07 7.07
pKa 9.6 9.6
Polar surface area 29.46 29.46
Solubility (μg/mL) 0.26 ± 0.03 1 – 2