Reagent or Resource	Source and Identifier
Antibodies
Anti-BrdU, FITC, clone PRB-1	(BioLegend Cat# 515406, RRID:AB_2566333)
Anti-human GzB, A647, clone GB11	(BioLegend Cat# 515403, RRID:AB_2114575)
Anti-human GzB, FITC, clone GB11	(BioLegend Cat# 103204, RRID:AB_312989)
Anti-mouse B220, biotinylated, clone RA3-6B2	(BioLegend Cat# 107005, RRID:AB_313300)
Anti-mouse CCR5 PE, clone HMCCR5	(BioLegend Cat# 121606, RRID:AB_572007)
Anti-mouse CD11b, biotinylated, clone M1/70	(BioLegend Cat# 101204, RRID:AB_312787)
Anti-mouse CD11c, PE, clone N418	(BioLegend Cat# 117308, RRID:AB_313777)
Anti-mouse CD16/CD32, clone 93	(BioLegend Cat# 101302, RRID:AB_312801)
Anti-mouse CD3, FITC, clone 145-2C11	(BioLegend Cat# 100306, RRID:AB_312671)
Anti-mouse CD4, BV605, clone GK 1.5	(BioLegend Cat# 100451, RRID:AB_2564591)
Anti-mouse CD4, PE, clone GK 1.5	(BioLegend Cat# 100408, RRID:AB_312693)
Anti-mouse CD44, FITC, clone IM7	(BD Biosciences Cat# 553133, RRID: AB_2076224)
Anti-mouse CD45.1, PB, clone A20	(BioLegend Cat# 110722, RRID:AB_492866)
Anti-mouse CD45.2, APC-Cy7, clone 104	(BioLegend Cat# 109824, RRID:AB_830789)
Anti-mouse CD62L, PE, clone MEL-14	(BioLegend Cat# 104407, RRID:AB_313094)
Anti-mouse CD8a, biotinylated, clone 53-6.7	(BD Biosciences Cat# 553029, RRID:AB_394567)
Anti-mouse CD8a, PE, clone 53-6.7	(BioLegend Cat# 100708, RRID:AB_312747)
Anti-mouse CD8a, PE-Cy7, clone 53-6.7	(BioLegend Cat# 100722, RRID:AB_312761)
Anti-mouse IFNg, PE-Cy7, clone XMG1.2	(BioLegend Cat# 505826, RRID:AB_2295770)
Anti-mouse IFNg, APC, clone XMG1.2	(BioLegend Cat# 505810, RRID:AB_315404)
Anti-mouse IL-1R1, PE, clone JAMA147	(BioLegend Cat# 113505, RRID:AB_2125036)
Anti-mouse IL-18Ra, APC, clone BG/IL18RA	(BioLegend Cat# 132903, RRID:AB_2123952)
Anti-mouse NK1.1, biotinylated, clone PK136	(BD Biosciences Cat# 553163, RRID:AB_394675)
Anti-mouse Tbet, PE, clone 4B10	(BioLegend Cat# 644810, RRID:AB_2200542)
Anti-mouse TCRb, BV421, clone H57-597	(BioLegend Cat# 109229, RRID:AB_10933263)
Anti-mouse TCRgd, biotinylated, clone GL3	(BD Biosciences Cat# 553176, RRID:AB_394687)
Streptavidin, PE	(BioLegend Cat# 133505, RRID:AB_1626229)
Streptavidin, PE-Cy7	(BD Biosciences Cat# 554061, RRID:AB_10053328)
Chemicals, Peptides
2-mercaptoethanol	SIGMA-Aldrich Cat# M6250
5-Bromo-2'-deoxyuridine (BrdU)	SIGMA-Aldrich Cat# B8434
Collagenase Tipo IV	SIGMA-Aldrich Cat# C5138-16
DNAse I	SIGMA-Aldrich Cat# DN25-16
Guanidine thiocyanate	SIGMA-Aldrich Cat# 69277-2506
Monensin	SIGMA-Aldrich Cat# 22373-78-0
Paraformaldehyde	SIGMA-Aldrich Cat# 30525-89-4
Saponin	SIGMA-Aldrich Cat# 54521
Sodium azide	SIGMA-Aldrich Cat# 52002-1006
Trizol	Ambion-LifeTechnologies Cat# 15596018
Tskb20 peptide	Genscript
Tween 20	Biorad Cat# 170-6531
RPMI media	GIBCO Cat# 22400-071
Fetal calf serum	GIBCO Cat# 12657-029
PBS - Phosphate-Buffered Saline	GIBCO Cat# 10010031
Critical commercial assays
SYBR™ Green PCR Master Mix	Applied Biosystems Cat# 4309155
IL-1beta/IL-1F2 DuoSet ELISA kit	R&D Systems Cat# DY401
IL-18/IL-1F4 ELISA kit	R&D Systems Cat# 7625
Dynabeads Biotin Binder	Invitrogen Cat# 11047
Illumina MouseRef-8 v2.0 Expression BeadChips	Illumina Cat# BD-202-0202
Experimental models: Organisms/Strains
Mouse: C57BL/6	RRID:IMSR_JAX:000664
Mouse: B6.SJL	RRID:IMSR_JAX:002014
Mouse: B6 x B6.SJL (F1)	animal house at UFF, Niteroi, BR
Mouse: Myd88-/-	RRID:MGI:5447806
Mouse: IL18r1	RRID:IMSR_JAX:004131
Mouse: IL1r1-/-	RRID:IMSR_JAX:003245
Mouse: Rag2-/-	RRID:IMSR_JAX:008449
Trypanosoma cruzi	NCBI Taxon ID:5693
Oligonucleotides
Primers for qPCR	IDT - Integrated DNA Technologies
Deposited data
Microarray	This paper GEO: GSE57738
Software
Summit V4.3 software	Dako Colorado, Inc
GeneSpring software GX 11.0	Agilent Technologies
GraphPad Prism version 5 for Windows	GraphPad Software
GEO2R	NCBI NIH http://ncbi.nlm.nih.gov/geo/geo2r/