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IR Isoform Relative Abundance in Various Conditions With Insulin Resistance and Hyperinsulinemia
| Disorder | Model | IR-A/IR-B Ratio | References |
|---|---|---|---|
| Obesity | Adipocytes | ⇧ | |
| Kaminska et al. (86) | |||
| Adipocytes after weight loss | ⇩ | ||
| T2DM | Liver | ⇧ | |
| Besic et al. (87) | |||
| Liver after weight loss only when diabetes remission is present | ⇩ | ||
| Gestational diabetes | HUVECs | ⇧ | Westermeier et al. (222) |
| Myotonic dystrophy | Skeletal muscle | ⇧ | Santoro et al. (382) |
