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. 2017 May 17;17(3):363–370. doi: 10.1007/s40268-017-0184-x

Table 3.

Pharmacokinetic parameters of oxycodone after a single oral dose of test and reference tablet (10 mg) under fed conditions in healthy male Japanese subjects (study 2)

Variables Test (N = 24) Reference (N = 23)
C max (ng/ml) 17.0 (18.8) 15.0 (17.2)
AUCt (ng·h/ml) 156 (16.5) 156 (19.8)
AUCinf (ng·h/ml) 157 (16.7) 158 (20.1)
t max (h) 4.50 (2.00; 5.50) 3.50 (2.00; 5.00)
t ½ (h) 4.26 ± 0.574 5.45 ± 0.676

Values are geometric mean (%CV), except for t max, which is presented as median (minimum; maximum), and t ½, which is presented as arithmetic mean ± standard deviation

AUC inf AUC up to infinity, AUC t area under the plasma concentration–time curve to the last sampling time, C max maximum plasma concentration, %CV coefficient of variation, t max time to reach maximum concentration, t ½ terminal elimination half-life