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. 2017 May 17;17(3):363–370. doi: 10.1007/s40268-017-0184-x
This bioequivalence study demonstrates that the pharmacokinetic properties of a newly formulated extended-release oxycodone 10-mg tablet are bioequivalent to a marketed reference product under fasting and fed conditions.
Both treatments were well tolerated when taken without an opioid antagonist in healthy Japanese subjects.
Hydrophilic matrix technology is one of the proper methods to manufacture an oxycodone extended-release formulation.