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. 2017 Jun 1;17(3):381–388. doi: 10.1007/s40268-017-0187-7
The recommended dosage for the Phase II study was 350 mg/m2/day in combination with 800 mg of sorafenib daily.
The disease control rate was 75% in this Phase I study.
Combination therapy with sorafenib and 5-FU appears to be well tolerated and may have the potential of an option for advanced HCC.