Table 3.
Clinical data at dialysis initiation
| Clinical data | CERA (n = 37) | DA (n = 26) | P value |
|---|---|---|---|
| RBC count (×106/μL) | 3.32 ± 0.50 | 2.91 ± 0.36 | 0.0003 |
| Hb level (g/dL) | 9.82 ± 1.52 | 8.79 ± 1.07 | 0.003 |
| MCV (fL) | 89.93 ± 7.03 | 91.34 ± 4.92 | 0.24 |
| Ret count (×104/μL) | 5.21 ± 2.95 | 3.15 ± 1.62 | 0.004 |
| Alb (g/dL) | 3.34 ± 0.67 | 3.38 ± 0.61 | 0.80 |
| BUN (mg/dL) | 88.78 ± 30.74 | 90.04 ± 19.51 | 0.83 |
| Cr (mg/dL) | 7.71 ± 2.38 | 8.75 ± 3.25 | 0.076 |
| TSAT (%) | 28.62 ± 16.71 | 30.10 ± 11.85 | 0.72 |
| Ferritin (ng/mL) | 139.80 ± 115.62 | 162.00 ± 97.24 | 0.56 |
| Patients with low TSAT (≤20%) and low ferritin (≤100 ng/mL) (%) | 16.7 | 5.6 | 0.37 |
| CRP (mg/dL) | 0.95 ± 1.84 | 1.48 ± 4.14 | 0.39 |
| eGFR (mL/min/1.73 m2) | 6.11 ± 2.79 | 5.67 ± 2.36 | 0.53 |
| ESA dosage (μg/4 weeks) | 92.87 ± 63.29 | 109.15 ± 61.94 | 0.23 |
| ERI (μg/kg/g/dL/4 weeks) | 0.171 ± 0.130 | 0.200 ± 0.119 | 0.38 |
| CTR (%) | 53.01 ± 5.32 | 53.66 ± 6.66 | 0.67 |
| Iron administration (%) | 32.4 | 11.5 | 0.07 |
| Patients with Hb ≥10 g/dL (%) | 48.6 | 19.2 | 0.02 |
Values are given as mean ± standard deviation for continuous variables and frequency (%) for nominal variables
Alb albumin, BUN blood urea nitrogen, CERA continuous erythropoietin receptor activator, Cr creatinine, CRP C-reactive protein, CTR cardiothoracic ratio, DA darbepoetin-α, eGFR estimated glomerular filtration rate, ERI erythropoietin resistance index, ESA erythropoiesis-stimulating agent, Hb hemoglobin, MCV mean corpuscular volume, Ret reticulocyte, RBC red blood cell, TSAT transferrin saturation