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. 2017 Jun 23;17(3):475–480. doi: 10.1007/s40268-017-0193-9

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Effects of various drugs on the binding of S-disopyramide, S-warfarin, and tamsulosin to human α1-acid glycoprotein (only typical patterns are presented). a Effect of aprindine on the binding of S-dispyramide. b Effect of aprindine on the binding of S-warfarin. c Effect of simvastatin on the binding of tamsulosin [rhombus: control, square: with test drug (9.62 µM), triangle: with test drug (19.2 µM), circle: with test drug (48.1 µM)]