Fig. 7.

Effect of other anti-epileptic drugs on eslicarbazepine acetate. When eslicarbazepine acetate is co-administered with carbamazepine, phenobarbital, or phenytoin, the dose of eslicarbazepine acetate may need to be increased because these drugs increase clearance of eslicarbazepine acetate. However, co-administration of eslicarbazepine acetate with gabapentin, lamotrigine, levitiracetam, topiramate, or valproate does not require any ESL dosage adjustments. Data obtained from Aptiom prescribing information [33]. CI confidence interval