Table 3.
MicroRNA-convergent fusions involving precursors of upregulated miRNAs
| miRNA | Number 5′ partner genes | Number tumors with more than one 5′ partner | Number tumors 3′ fusion | Host gene | Cytogenetic location |
|---|---|---|---|---|---|
| hsa-mir-21 | 20 | 2 | 19 | VMP1 | 17q23.1 |
| hsa-mir-25, hsa-mir-93, hsa-mir-106b | 12 | 1 | 14 | MCM7 | 7q22.1 |
| hsa-mir-26a-1 | 3 | 0 | 3 | CTDSPL | 3p22.2 |
| hsa-mir-26b | 3 | 0 | 3 | CTDSP1 | 2q35 |
| hsa-mir-33b, hsa-mir-6777 | 62 | 19 | 82 | SREBF1 | 17p11.2 |
| hsa-mir-151a | 11 | 2 | 11 | PTK2 | 8q24.3 |
| hsa-mir-340 | 4 | 0 | 4 | RNF130 | 5q15 |
| hsa-mir-342 | 38 | 11 | 34 | EVL | 14q32.2 |
| hsa-mir-483 | 107 | 17 | 49 | IGF2 | 11p15.5 |
| hsa-mir-548ah, hsa-mir-4450 | 6 | 0 | 6 | SHROOM3 | 4q21.1 |
| hsa-mir-548ao | 5 | 0 | 5 | SFRP1 | 8p11.21 |
| hsa-mir-629 | 8 | 0 | 14 | TLE3 | 15q23 |
| hsa-mir-641 | 2 | 0 | 2 | AKT2 | 19q13.2 |
| hsa-mir-675 | 5 | 1 | 6 | H19 | 11p15.5 |
| hsa-mir-1229 | 4 | 1 | 3 | MGAT4B | 5q35.3 |
| hsa-mir-1249 | 6 | 2 | 29 | KIAA0930 | 22q13.31 |
| hsa-mir-1343 | 2 | 0 | 2 | PDHX | 11p13 |
| hsa-mir-3145 | 5 | 0 | 5 | NHSL1 | 6q23.3 |
| hsa-mir-3194 | 4 | 0 | 4 | NFATC2 | 20q13.2 |
| hsa-mir-3616 | 5 | 0 | 5 | EYA2 | 20q13.12 |
| hsa-mir-3909 | 3 | 0 | 3 | TOM1 | 22q12.3 |
| hsa-mir-4714 | 103 | 6 | 29 | IGF1R | 15q26.3 |
| hsa-mir-4728 | 338 | 92 | 155 | ERBB2 | 17q12 |
| hsa-mir-4802 | 5 | 0 | 5 | RBM47 | 4p14 |
| hsa-mir-6510 | 22 | 5 | 24 | KRT15 | 17q21.2 |
MicroRNA-convergent fusions involving the precursors of miRNAs upregulated in tumors with 3ʹ host fusions vs tumors without host gene fusions (mature miRNAs are listed in Supplementary Table 3). For clustered miRNAs, all miRNA loci included in the host gene fusions are listed